Suggested Use: 1-2 capsules per day, with a meal.
Folate 400 -
Folate 400 provides Metafolin® L-5-methyltetrahydrofolate (L-5MTHF), the naturally occurring, universally metabolized form of folate.
What Is It?
Folate is provided in this formula as Metafolin®, the naturally
occurring universally metabolized form of folate. Metafolin®
is chemically identical to the active folate metabolite,
5-methyltetrahydrofolate (L-5-MTHF). L-5-MTHF is the
predominant, naturally occurring form of folate in food.
Through bypassing several enzymatic activation steps, it is
directly usable by the body and provides all of the benefits
of folic acid regardless of functional or genetic variations.*
Uses For Folate 400
Cellular Health: An extensive body of evidence
indicates that adequate folate intake may provide
significant cardiovascular, cellular and neural protection.
However, genetic variations affecting activation
and metabolism of supplemental folic acid are highly
prevalent. Metafolin is a naturally occurring universally
metabolized and active form of folate, L-5-MTHF. As
such, it can be directly used in a diverse array of
essential methylation reactions. Additionally, clinical
evidence indicates that the bioavailability of
Metafolin is superior to folic acid. In a double-blind,
randomized, placebo-controlled intervention study of 144
women of child-bearing age, 5-MTHF supplementation
resulted in a greater accumulation of 5-MTHF in red
blood cells than equimolar doses of folic acid. Adequate
folate status is critical for nucleic acid synthesis and
neurotransmitter synthesis. At the molecular level, the
main function of folate is to donate methyl groups in key
biochemical reactions occurring in blood cells, neurons,
the vasculature and many other tissues.*
What Is The Source?
Metafolin®, L-5-methyltetrahydrofolate (L-5-MTHF) is
synthetic. Hypo-allergenic plant fiber is derived from pine
cellulose.
Metafolin® is a registered trademark of Merck KGaA,
Darmstadt, Germany
Recommendations
Pure Encapsulations recommends 1-2 capsules per day,
with a meal.
Are There Any Potential Side Effects Or
Precautions?
At this time, there are no known side effects or precautions.
If pregnant or lactating, consult your physician before
taking this product.
Are There Any Potential Drug Interactions?
Folic acid may adversely interact with chemotherapeutic
drugs. Consult your physician for more information.
Supplement Facts:Suggested Use: 1-2 capsules per day, with a meal.
| Ingredients | AMT | %DV |
|---|
| folate (as Metafolin®, L-5-MTHF) | 400 mcg. | - |
Other Ingredients: (hypo-allergenic plant fiber added to complete capsule volume)
(-) There is no %DV or the manufactuer has not provided this data.
Questions About This Product?
Phone us at 781-414-2434
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