For Assistance, Call 1-888-821-8808
Provider Site:  drkordonowy - (change)
Provider Information:
Website: drkordonowy
Business: Internal Medicine Lipid & Wellness Practice of Fort Myers
Phone: 239-362-3005
Home / Products / SAMe (S-Adenosylmethionine)

SAMe (S-Adenosylmethionine)

View all products by Pure Encapsulations
Ask a question
Size
-
+
FREE Shipping* on all orders over $89.00
Subscribe for Auto-Shipments & Get Ongoing Savings!
Auto Ship
Suggested Use: 1-2 capsules daily, in divided doses, between meals, or as directed by a health professional.

SAMe (S-Adenosylmethionine) - *Provides 200 mg per capsule of enhanced stability form SAMe; Manufactured using a solvent-free manufacturing process

What Is It?

SAMe (S-adenosylmethionine) is a metabolite present in all living cells. It functions as a donor of methyl groups in over 100 different reactions and contributes to the synthesis, activation and/or metabolism of hormones, neurotransmitters, nucleic acids, phospholipids and proteins. Research indicates support for positive mood, cell membrane fluidity, neurotransmitter synthesis, glutathione production, joint comfort and healthy cell growth.*

Uses For SAMe

Cellular Function: SAMe functions as a donor of methyl groups in over 100 different reactions catalyzed by methyltransferase enzymes. Methyl groups act as a signal throughout the body, regulating genetic expression and cellular function. Healthy methylation is vital for cellular health, hormone and neurotransmitter production and energy metabolism. SAMe also functions as a precursor molecule for glutathione and promotes polyamine synthesis. Clinical trials indicate that SAMe administration enhances glutathione production in hepatic tissue and red blood cells. The polyamines spermidine and spermine maintain healthy cell growth and cytokine balance.*

Cognitive Health:

Over 40 clinical studies indicate that SAMe promotes positive mood and cognitive function. In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood. While the exact mechanism for this benefit has not been determined, it is believed to support neurotransmitter monoamine synthesis and function, including dopamine and serotonin, through SAMe-dependent methylation reactions. It also promotes healthy protein turnover to support healthy CNS function and maintains healthy phospholipid methylation to support phosphatidylcholine production and cellular membrane integrity and fluidity.*

Joint Function:

Multiple clinical trials indicate that SAMe supports joint comfort and flexibility. In a meta-analysis involving 11 studies, SAMe offered statistically significant support for joint function. In another 16 week randomized double- blind placebo-controlled trial involving 56 subjects, SAMe offered statistically significant support for joint comfort. It is believed to enhance joint comfort and function by supporting proteoglycan synthesis, as well as helping to stabilize and protect the proteoglycans.*

What Is The Source?

SAMe is derived from fermentation. Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil. Hypo-allergenic plant fiber is derived from pine cellulose. Gellan gum is derived from Pseudomonas elodea.

Recommendations

Pure Encapsulations recommends 1-2 capsules daily, in divided doses, between meals, or as directed by your health care practitioner.

Are There Any Potential Side Effects Or Precautions?

Consult your healthcare provider before use if you are pregnant or nursing, taking antidepressant medication or if you have bipolar disorder. In rare cases, SAMe has been associated with flatulence, nausea, vomiting, diarrhea, constipation, dry mouth, headache, mild insomnia, anorexia, sweating, dizziness, and nervousness. Anxiety and tiredness have occurred in people with depression, and hypomania in people with bipolar disorder. Consult your physician for more information.

Are There Any Potential Drug Interactions?

SAMe is contra-indicated with anti-depressant medication, dextromethorphan, and meperidine (Demerol). Concurrent use might cause additive serotonergic effects and serotonin syndrome-like effects. It is also contra-indicated with Levodopa. Consult your physician for more information.

Supplement Facts:
Suggested Use: 1-2 capsules daily, in divided doses, between meals, or as directed by a health professional.
each vegetarian capsule contains:
IngredientsAMT%DV
SAMe (S-adenosylmethionine) (from S-adenosyl-L-methionine disulphate tosylate)200 mg-
Other Ingredients: calcium chloride, calcium oxide, hypo-allergenic plant fiber (cellulose), vegetarian capsule (cellulose, gellan gum, water) professional before use if you are pregnant or nursing, taking antidepressant medication or if you have bipolar disorder.
(-) There is no %DV or the manufactuer has not provided this data.
Questions About This Product?
Phone us at 239-362-3005
Online Health Care Connection:
Do you have questions about this product or would like to connect with your Health Care Provider? We are proud to offer Virtual Visit.
Get Healthy With Virtual Visit!
Your health care professional will be able to provide you with tailored product recommendations, advice, and exclusive promotions to help save you money on professionally formulated, high potency natural health products not found in stores.
Don't have an account or would like to learn more about Virtual Visit technology?
Sign up here!
Related Products:

Shop All Products

Office Location and Hours:
Internal Medicine Lipid & Wellness Practice of Fort Myers
6160 Winkler Road 
Fort Myers, FL, 33919, 
    Contact Us
Office Hours - notes
Mon:8:30 - 4:30
Tue:8:30 - 4:30
Wed:8:30 - 4:30
Thu:8:30 - 4:30
Fri:8:30 - 2:30
Sat: Closed
Sun:Closed
Browse Categories: